The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2012
Filed:
Dec. 10, 2004
Peter G. Schultz, La Jolla, CA (US);
Lei Wang, San Diego, CA (US);
John Christopher Anderson, San Diego, CA (US);
Jason Chin, Cambridge, GB;
David R. Liu, Lexington, MA (US);
Thomas J. Magliery, North Haven, CT (US);
Eric L. Meggers, Philadelphia, PA (US);
Ryan Aaron Mehl, Lancaster, PA (US);
Miro Pastrnak, San Diego, CA (US);
Steven William Santoro, Cambridge, MA (US);
Zhiwen Zhang, San Diego, CA (US);
Peter G. Schultz, La Jolla, CA (US);
Lei Wang, San Diego, CA (US);
John Christopher Anderson, San Diego, CA (US);
Jason Chin, Cambridge, GB;
David R. Liu, Lexington, MA (US);
Thomas J. Magliery, North Haven, CT (US);
Eric L. Meggers, Philadelphia, PA (US);
Ryan Aaron Mehl, Lancaster, PA (US);
Miro Pastrnak, San Diego, CA (US);
Steven William Santoro, Cambridge, MA (US);
Zhiwen Zhang, San Diego, CA (US);
The Scripps Research Institute, LaJolla, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.