The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2012
Filed:
Jun. 18, 2007
Marc-andré Theoleyre, Paris, FR;
Stanislas Baudouin, Aubergenville, FR;
Annick Merrien, Poissy, FR;
Eric Valery, Pulnoy, FR;
Olivier Ludemann-hombourger, Pompey, FR;
David Laurent, Nancy, FR;
Margit Holzer, Dommartement, FR;
Marc-André Theoleyre, Paris, FR;
Stanislas Baudouin, Aubergenville, FR;
Annick Merrien, Poissy, FR;
Eric Valery, Pulnoy, FR;
Olivier Ludemann-Hombourger, Pompey, FR;
David Laurent, Nancy, FR;
Margit Holzer, Dommartement, FR;
Groupe Novasep, Pompey, FR;
Abstract
A process is disclosed for separating biomolecules from an aqueous solution containing the biomolectules and impurities, having different affinities and/or interactions with a solid support. The solution is passed over a fixed bed of chromatographic resin containing at least three zones, with flow of liquid being arranged between adjacent zones and between a last and first zone. Each of several sequences includes at least an adsorption stage, a rinsing stage, or a desorption stage, with each subsequent sequence being carried out by a downstream displacement of fronts in the zones by approximately the same increment before the periodical displacement of the introduction and withdrawal points.