The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2012
Filed:
Apr. 08, 2004
Jeff Chen, San Francisco, CA (US);
Lisa Esther Dalrymple, San Francisco, CA (US);
Sergey Epshteyn, Fremont, CA (US);
Timothy Patrick Forsyth, Hayward, CA (US);
Tai Phat Huynh, Oakland, CA (US);
James William Leahy, San Leandro, CA (US);
Brian Hugh Ridgway, Belmont, CA (US);
Grace Mann, Brisbane, CA (US);
Larry W. Mann, Richland, MI (US);
Craig Stacy Takeuchi, Burlingame, CA (US);
Joan C. Sangalang, Mountain View, CA (US);
Jeff Chen, San Francisco, CA (US);
Lisa Esther Dalrymple, San Francisco, CA (US);
Sergey Epshteyn, Fremont, CA (US);
Timothy Patrick Forsyth, Hayward, CA (US);
Tai Phat Huynh, Oakland, CA (US);
James William Leahy, San Leandro, CA (US);
Brian Hugh Ridgway, Belmont, CA (US);
Grace Mann, Brisbane, CA (US);
Larry W. Mann, Richland, MI (US);
Craig Stacy Takeuchi, Burlingame, CA (US);
Joan C. Sangalang, Mountain View, CA (US);
Exelixis, Inc., South San Francisco, CA (US);
Abstract
The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Tie-2. Methods of using the compounds and pharmaceutical compositions thereof to treat kinase-dependent diseases and conditions are also an aspect of the invention.