The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2012

Filed:

Jun. 09, 2008
Applicants:

Michele Potashman, Cambridge, MA (US);

Tae-seong Kim, Thousand Oaks, CA (US);

Steven Bellon, Wellesley, MA (US);

Shon Booker, Thousand Oaks, CA (US);

Yuan Cheng, Newbury Park, CA (US);

Joseph L. Kim, Wayland, MA (US);

Andrew Tasker, Simi Valley, CA (US);

Ning Xi, Thousand Oaks, CA (US);

Shimin Xu, San Diego, CA (US);

Jean-christophe Harmange, Andover, MA (US);

George Borg, Somerville, MA (US);

Matthew Weiss, Boston, MA (US);

Brian L. Hodous, Cambridge, MA (US);

Russell Graceffa, Hampton, NH (US);

William H. Buckner, Kittery, ME (US);

Craig E. Masse, Cambridge, MA (US);

Deborah Choquette, Medford, MA (US);

Matthew W. Martin, Arlington, MA (US);

Julie Germain, Quebec, CA;

Lucian V. Dipietro, Gloucester, MA (US);

Stuart C. Chaffee, Boston, MA (US);

Joseph J. Nunes, Andover, MA (US);

John L. Buchanan, Newton, MA (US);

David C. Mcgowan, Brussels, BE;

Douglas A. Whittington, Waltham, MA (US);

Gregory J. Habgood, Merrimac, MA (US);

Vinod F. Patel, Acton, MA (US);

Daniel LA, Brookline, MA (US);

Inventors:

Michele Potashman, Cambridge, MA (US);

Tae-Seong Kim, Thousand Oaks, CA (US);

Steven Bellon, Wellesley, MA (US);

Shon Booker, Thousand Oaks, CA (US);

Yuan Cheng, Newbury Park, CA (US);

Joseph L. Kim, Wayland, MA (US);

Andrew Tasker, Simi Valley, CA (US);

Ning Xi, Thousand Oaks, CA (US);

Shimin Xu, San Diego, CA (US);

Jean-Christophe Harmange, Andover, MA (US);

George Borg, Somerville, MA (US);

Matthew Weiss, Boston, MA (US);

Brian L. Hodous, Cambridge, MA (US);

Russell Graceffa, Hampton, NH (US);

William H. Buckner, Kittery, ME (US);

Craig E. Masse, Cambridge, MA (US);

Deborah Choquette, Medford, MA (US);

Matthew W. Martin, Arlington, MA (US);

Julie Germain, Quebec, CA;

Lucian V. DiPietro, Gloucester, MA (US);

Stuart C. Chaffee, Boston, MA (US);

Joseph J. Nunes, Andover, MA (US);

John L. Buchanan, Newton, MA (US);

David C. McGowan, Brussels, BE;

Douglas A. Whittington, Waltham, MA (US);

Gregory J. Habgood, Merrimac, MA (US);

Vinod F. Patel, Acton, MA (US);

Daniel La, Brookline, MA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.


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