The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2012

Filed:

Nov. 30, 2009
Applicants:

Daniela Alberati, Zofingen, CH;

Luca Gobbi, Muttenz, CH;

Matthias Koerner, Grenzach-Wyhlen, DE;

Bernd Kuhn, Reinach, CH;

Jens-uwe Peters, Grenzach-Wyhlen, DE;

Rosa Maria Rodriguez-sarmiento, Basel, CH;

Mark Rogers-evans, Bottmingen, CH;

Markus Rudolph, Basel, CH;

Inventors:

Daniela Alberati, Zofingen, CH;

Luca Gobbi, Muttenz, CH;

Matthias Koerner, Grenzach-Wyhlen, DE;

Bernd Kuhn, Reinach, CH;

Jens-Uwe Peters, Grenzach-Wyhlen, DE;

Rosa Maria Rodriguez-Sarmiento, Basel, CH;

Mark Rogers-Evans, Bottmingen, CH;

Markus Rudolph, Basel, CH;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is concerned with novel pyridazinones of formula (I) wherein R, R, Rand Rare as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used for the treatment of CNS disorders.


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