The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2012

Filed:

Nov. 05, 2009
Applicants:

Tomasz Glinka, Cupertino, CA (US);

Olga Rodny, Mountain View, CA (US);

Keith A. Bostian, Atherton, CA (US);

David M. Wallace, San Diego, CA (US);

Robert I. Higuchi, Solana Beach, CA (US);

Chun Chow, San Diego, CA (US);

Chi Ching Mak, San Diego, CA (US);

Gavin Hirst, San Diego, CA (US);

Brian Eastman, San Diego, CA (US);

Inventors:

Tomasz Glinka, Cupertino, CA (US);

Olga Rodny, Mountain View, CA (US);

Keith A. Bostian, Atherton, CA (US);

David M. Wallace, San Diego, CA (US);

Robert I. Higuchi, Solana Beach, CA (US);

Chun Chow, San Diego, CA (US);

Chi Ching Mak, San Diego, CA (US);

Gavin Hirst, San Diego, CA (US);

Brian Eastman, San Diego, CA (US);

Assignee:

Rempex Pharmaceuticals, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds having polybasic functionalities. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.


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