The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2012
Filed:
Sep. 28, 2001
Masking of the background fluorescence and luminescence in the optical analysis of biomedical assays
Thoams Krahn, Hagen, DE;
Wolfgang Paffhausen, Leverkusen, DE;
Andreas Schade, Essen, DE;
Martin Bechem, Wuppertal, DE;
Delf Schmidt, Wuppertal, DE;
Thoams Krahn, Hagen, DE;
Wolfgang Paffhausen, Leverkusen, DE;
Andreas Schade, Essen, DE;
Martin Bechem, Wuppertal, DE;
Delf Schmidt, Wuppertal, DE;
Bayer Healthcare AG, Leverkusen, DE;
Abstract
A process for the quantitative optical analysis of fluorescently labeled biological cells involves contacting a cell layer on a transparent support at the bottom of a reaction vessel with a solution containing the fluorescent dye. This process can also be used for improving the sensitivity in the quantitative optical analysis of a luminescent biological cell layer. Analogously, these process principles can also be used in receptor studies for the masking of the interfering background radiation in the quantitative optical analysis of fluorescently or luminescently labelled reaction components. In this case, a receptor layer at the bottom of a reaction vessel is in contact with a solution in which a fluorescent or luminescent ligand is dissolved.