The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2012
Filed:
May. 01, 2008
Thomas M. Roberts, Cambridge, MA (US);
Jean Zhao, Brookline, MA (US);
David E. Hill, Arlington, MA (US);
William C. Hahn, Newton, MA (US);
Jesse Boehm, Jamaica Plain, MA (US);
Thomas M. Roberts, Cambridge, MA (US);
Jean Zhao, Brookline, MA (US);
David E. Hill, Arlington, MA (US);
William C. Hahn, Newton, MA (US);
Jesse Boehm, Jamaica Plain, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Abstract
Provided herein are nucleic acids, proteins, vectors, cells, kits, devices and methods useful for identifying regulatable proteins that are able to complement components of cellular signaling pathways. Also provided are compositions and methods using these complementing genes directly as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics. Further provided are methods for using changes caused by expression of the complementing genes to indirectly identify associated genes to be used as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics.