The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2012
Filed:
Apr. 21, 2006
John B. Buse, Chapel Hill, NC (US);
Kathleen Dungan, Columbus, OH (US);
Steven D. Wittlin, Rochester, NY (US);
Eric A. Button, Kannapolis, NC (US);
Shuhei Kato, Tokyo, JP;
Toshio Tanabe, Tokyo, JP;
John B. Buse, Chapel Hill, NC (US);
Kathleen Dungan, Columbus, OH (US);
Steven D. Wittlin, Rochester, NY (US);
Eric A. Button, Kannapolis, NC (US);
Shuhei Kato, Tokyo, JP;
Toshio Tanabe, Tokyo, JP;
Nippon Kayaku Kabushiki Kaisha, Tokyo, JP;
Toyota Tsusho America, Inc., New York, NY (US);
Abstract
The invention is a method of measuring blood glucose excursions in general, and postprandial hyperglycemia in diabetic patients in particular, by the 1,5-anhydroglucitol assay (1,5-AG) or A1C/1,5-AG assay combination. 1,5-AG levels and percent changes of 1,5-AG levels in short period are indicative of differing postmeal glucose levels in moderately-controlled diabetic patients with similar A1C levels. Thereby 1,5-AG assay is useful to identify diabetic patients who may be at risk for cardiovascular complications which would not be identifiable by A1C levels alone. Furthermore, ratios of A1C divided by 1,5-AG in each patient are superior indicators to 1,5-AG levels.