The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2012

Filed:

Oct. 17, 2007
Applicants:

Ying Buechler, Carlsbad, CA (US);

Ricky Lieu, San Diego, CA (US);

Michael Ong, San Diego, CA (US);

Stuart Bussell, Carlsbad, CA (US);

Nick Knudsen, San Diego, CA (US);

Ho Sung Cho, San Diego, CA (US);

Inventors:

Ying Buechler, Carlsbad, CA (US);

Ricky Lieu, San Diego, CA (US);

Michael Ong, San Diego, CA (US);

Stuart Bussell, Carlsbad, CA (US);

Nick Knudsen, San Diego, CA (US);

Ho Sung Cho, San Diego, CA (US);

Assignee:

Ambrx, Inc., La Jolla, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/27 (2006.01); A61K 38/18 (2006.01); A61K 39/00 (2006.01); C07K 1/14 (2006.01); C07K 1/16 (2006.01); C07K 1/18 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encoded amino acids and hGH from recombinant host cells or culture medium including, for example, yeast, insect, mammalian and bacterial host cells. The process of the present invention is also useful for purification of hGH linked to polymers or other molecules.


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