The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2012

Filed:

Dec. 17, 2008
Applicants:

Nicolas Bertheleme, Harlow, GB;

Wai Ngor Chan, Harlow, GB;

Jaqueline Sandra Scott, Harlow, GB;

Simon E. Ward, Harlow, GB;

Inventors:

Nicolas Bertheleme, Harlow, GB;

Wai Ngor Chan, Harlow, GB;

Jaqueline Sandra Scott, Harlow, GB;

Simon E. Ward, Harlow, GB;

Assignee:

Glaxo Group Limited, Greenford, Middlesex, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 211/72 (2006.01); C07D 213/62 (2006.01); C07C 303/00 (2006.01); A61K 31/44 (2006.01); A61K 31/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula (I) and salts thereof are provided: wherein n is 0, 1, 2 or 3; Ris selected from phenyl and pyridyl, each of which is optionally substituted by one or two groups independently selected from Calkyl and halogen; and Ris selected from H and CHwhen n is 1 and Ris H when n is 2 or 3. Processes for preparation, pharmaceutical compositions, and uses thereof as a medicament, for example in the treatment of a disease or condition mediated by a reduction or imbalance in glutamate receptor function, such as schizophrenia or cognition impairment, are also disclosed.


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