The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 08, 2012
Filed:
Jun. 13, 2008
Rogelio Siles, Baltimore, MD (US);
Ming Zhou, Coppell, TX (US);
J. Freeland Ackley, Erie, PA (US);
Kevin G. Pinney, Woodway, TX (US);
Shen-en Chen, Waco, TX (US);
Wara Milenka Arispe-angulo, Waco, TX (US);
Mary Lynn Trawick, Woodway, TX (US);
Rogelio Siles, Baltimore, MD (US);
Ming Zhou, Coppell, TX (US);
J. Freeland Ackley, Erie, PA (US);
Kevin G. Pinney, Woodway, TX (US);
Shen-En Chen, Waco, TX (US);
Wara Milenka Arispe-Angulo, Waco, TX (US);
Mary Lynn Trawick, Woodway, TX (US);
Baylor University, Waco, TX (US);
Abstract
The present invention relates to semicarbazone or thiosemicarbazone inhibitors of cysteine proteases and methods of using such compounds to prevent and treat protozoan infections such as trypanosomiasis, malaria and leishmaniasis. The compounds also find use in inhibiting cysteine proteases associated with carcinogenesis, including cathepsins B and L.