The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2012

Filed:

Jun. 01, 2007
Applicants:

Song LI, Beijing, CN;

Wu Zhong, Beijing, CN;

Junhai Xiao, Beijing, CN;

Xinghai MA, Beijing, CN;

Lili Wang, Beijing, CN;

Hongying Liu, Beijing, CN;

Zhibing Zheng, Beijing, CN;

Inventors:

Song Li, Beijing, CN;

Wu Zhong, Beijing, CN;

Junhai Xiao, Beijing, CN;

Xinghai Ma, Beijing, CN;

Lili Wang, Beijing, CN;

Hongying Liu, Beijing, CN;

Zhibing Zheng, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 295/185 (2006.01); A61K 31/54 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to N-Substituted thiomorpholine compounds of formula I, the possible isomers, the pharmaceutically acceptable salts, the solvates, the hydrates or the prodrugs thereof as inhibitors of dipeptidyl peptidase IV (DPP-IV); and to a method for preparing the compounds of formula I, pharmaceutical compositions comprising the compounds of formula I and use of the compounds of formula II in medical field, particularly in the preparation of medicaments for treating and preventing diabetes (in particular type II diabetes), hyperglycemia, X syndrome, hyperinsulinemia, obesity, atherosclerosis and all kinds of diseases modulated by immune system.


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