The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 08, 2012
Filed:
Apr. 05, 2010
Barton James Bradbury, Wallingford, CT (US);
Milind Deshpande, Madison, CT (US);
Akihiro Hashimoto, Branford, CT (US);
Ha Young Kim, Cheshire, CT (US);
Edlaine Lucien, New Haven, CT (US);
Godwin Pais, Hamden, CT (US);
Michael Pucci, Kensington, CT (US);
Qiuping Wang, Bethany, CT (US);
Jason Allan Wiles, Hamden, CT (US);
Avinash Phadke, Branfod, CT (US);
Barton James Bradbury, Wallingford, CT (US);
Milind Deshpande, Madison, CT (US);
Akihiro Hashimoto, Branford, CT (US);
Ha Young Kim, Cheshire, CT (US);
Edlaine Lucien, New Haven, CT (US);
Godwin Pais, Hamden, CT (US);
Michael Pucci, Kensington, CT (US);
Qiuping Wang, Bethany, CT (US);
Jason Allan Wiles, Hamden, CT (US);
Avinash Phadke, Branfod, CT (US);
Achillion Pharmaceuticals, Inc., New Haven, CT (US);
Abstract
Disclosed herein are hydroxylthienoquinolones and related compounds and their pharmaceutically acceptable salts useful as antiviral agents and having the general formula in which the variables R, R, and Rare defined herein. Certain compounds provided herein possess potent antibacterial, antiprotozoal, or antifungal activity and are particularly efficacious for the treatment of MRSA infections. The invention also provides pharmaceutical compositions, pharmaceutical compositions containing a hydroxylthienoquinolone in combination with one or more other active agent, and methods of treating microbial infections in animals by administering an effective amount of a hydroxylthienoquinolone or related compound to an animal suffering from a microbial infection.