The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8173405 B1

PDF
Full Text
Expired
Date of Patent:
May. 08, 2012

Filed:

Dec. 12, 2007
Applicants:

Caroline Virginia Mcneil, Houston, TX (US);

Pietro Morlacchi, Houston, TX (US);

Alyssa Baevich, Richmond, TX (US);

Seiichi Paul Tillich Matsuda, Houston, TX (US);

Inventors:

Caroline Virginia McNeil, Houston, TX (US);

Pietro Morlacchi, Houston, TX (US);

Alyssa Baevich, Richmond, TX (US);

Seiichi Paul Tillich Matsuda, Houston, TX (US);

Assignee:

William Marsh Rice University, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

According to one embodiment, the description relates to a method of nerolidol production. The method includes culturing a yeast strain lacking functional squalene synthase and overproducing HMG CoA reductase in synthetic medium lacking uracil and producing nerolidol. The pH of the medium may be adjusted to an acidic level to further increase nerolidol production. Other chemicals may also be produced by this method. The nerolidol or other chemicals may be removed from the yeast or medium or both. The medium may additionally contain a polyaromatic resin, which may adsorb nerolidol or other chemicals.


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