The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2012
Filed:
Mar. 24, 2008
Manne Satyanarayana Reddy, Hyderabad, IN;
Srinivasan Thirumalai Rajan, Hyderabad, IN;
Sajja Eswaraiah, Hyderabad, IN;
Revu Satyanarayana, East Godavari, IN;
Manne Satyanarayana Reddy, Hyderabad, IN;
Srinivasan Thirumalai Rajan, Hyderabad, IN;
Sajja Eswaraiah, Hyderabad, IN;
Revu Satyanarayana, East Godavari, IN;
MSN Laboratories, Limited, Andhra Pradesh Hyderabad, IN;
Abstract
The present invention encompasses novel intermediates of pregabalin, namely 3-cyano-5-methyl hexanamide (28) and 3-(amino methyl)-5 methyl hexanamide (29), and processes for their preparation. The invention also encompasses a process for converting the novel pregabalin intermediates into pregabalin, Formula (I): The present invention further provides a cost effective method for the synthesis of (S)-pregabalin, which involves the recovery of mandelic acid and tartaric acid used in the resolution process and recycling them, increasing the yields of the final product formed, which substantially reduced the cost of the production.