The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2012
Filed:
Jan. 11, 2011
Applicants:
Martin Gleave, Vancouver, CA;
Michael N. Pollak, Montreal, CA;
Randy J. Leavitt, Dollard-des-Ormeaux, CA;
Inventors:
Martin Gleave, Vancouver, CA;
Michael N. Pollak, Montreal, CA;
Randy J. Leavitt, Dollard-des-Ormeaux, CA;
Assignee:
The University of British Columbia, Vancouver, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
CNS malignancy is treated in a subject suffering from a CNS malignancy by administering to the subject an antisense oligonucleotide having a sequence of bases that is complementary to portions of both the gene encoding IGFBP-2 and the gene encoding IGFBP-5, and which is of sufficient length to act as an inhibitor of the effective amount of IGFBP-2 and IGFBP-5, in an amount effective to reduce effective levels of IGFBP-2 and IGFBP-5 in cells of the CNS malignancy.