The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2012
Filed:
Jun. 29, 2011
Applicants:
Jean Plouet, Paris, FR;
Monica Alemany, Paris, FR;
Inventors:
Jean Plouet, Paris, FR;
Monica Alemany, Paris, FR;
Assignees:
Centre National de la Recherche Scientifique, Paris, FR;
IVS Institut des Vaisseaux et du Sang, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 15/00 (2006.01); A01N 61/00 (2006.01); A61K 38/00 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01); C07H 1/00 (2006.01); C07H 5/04 (2006.01); C07H 5/06 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
A peptide fragment of the netrin-4 protein and nucleic acids coding for the peptide are described. The peptide can inhibit endothelial cell proliferation and cell migration, as well as activate the proliferation and migration of pericytes and smooth muscle cells. Pharmaceutical formulations containing the peptide and/or the nucleic acids can be used to treat a variety of tumoral and non-tumoral pathologies.