The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2012
Filed:
Jan. 07, 2009
Applicants:
Sabine Eming, Cologne, DE;
Thomas Krieg, Cologne, DE;
Stephan Sollberg, Schwerin, DE;
Gereon Lauer, Radolfzell, DE;
Inventors:
Sabine Eming, Cologne, DE;
Thomas Krieg, Cologne, DE;
Stephan Sollberg, Schwerin, DE;
Gereon Lauer, Radolfzell, DE;
Assignee:
Bayer Innovation GmbH, Duesseldorf, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/475 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to vascular endothelial growth factor (VEGF) in which the alanine at AA position 111 is replaced by proline. The arginine at AA position 110 may moreover be replaced by another amino acid. The invention also relates to derivatives of the VEGF according to the invention, nucleic acids, expression systems, medicaments and the use of the VEGF mutants of the invention for the treatment of chronic wounds.