The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2012
Filed:
Jan. 25, 2006
Lewis T. Williams, Mill Valley, CA (US);
Hongbing Zhang, Albany, CA (US);
Yan Wang, Redwood City, CA (US);
Loriane Masuoka, Oakland, CA (US);
Stephen Doberstein, San Francisco, CA (US);
Lewis T. Williams, Mill Valley, CA (US);
Hongbing Zhang, Albany, CA (US);
Yan Wang, Redwood City, CA (US);
Loriane Masuoka, Oakland, CA (US);
Stephen Doberstein, San Francisco, CA (US);
Five Prime Therapeutics, Inc., South San Francisco, CA (US);
Abstract
Pharmaceutical polypeptide compositions promote the survival of cardiac cells, recruit cardiac cells to the cardiac area, stimulate the differentiation of cardiac cells, stimulate the proliferation of cardiac cells, and promote the activity of cardiac cells, thereby treating cardiac conditions. Methods of providing these compositions to the cardiac area include catheterization and direct injection. In preferred embodiments, the compositions comprise one of more of the following growth factors: EGF, bFGF, cardiotrophin-1, thrombin, PDGF-BB, amphiregulin, epiregulin, HB-EGF, TGFalpha, betacellulin, heregulin alpha, NRG-1-beta1-HRG-beta1, FGF 9.