The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 01, 2012

Filed:

Nov. 24, 2006
Applicants:

Ugur Sahin, Mainz, DE;

Ozlem Tureci, Mainz, DE;

Dirk Usener, Wiesbaden, DE;

Stefan Fritz, Flonheim, DE;

Cristoph Uherek, Ginsheim, DE;

Gunda Brandenburg, Mainz, DE;

Harald-gerhard Geppert, Hannover, DE;

Anja Kristina Schroder, Mainz, DE;

Philippe Thiel, Planegg, DE;

Inventors:

Ugur Sahin, Mainz, DE;

Ozlem Tureci, Mainz, DE;

Dirk Usener, Wiesbaden, DE;

Stefan Fritz, Flonheim, DE;

Cristoph Uherek, Ginsheim, DE;

Gunda Brandenburg, Mainz, DE;

Harald-Gerhard Geppert, Hannover, DE;

Anja Kristina Schroder, Mainz, DE;

Philippe Thiel, Planegg, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.


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