The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 01, 2012

Filed:

Jul. 07, 2006
Applicants:

Albert Z. Kapikian, Rockville, MD (US);

Lone Simonsen, Chevy Chase, MD (US);

Timo Vesikari, Tampare, FI;

Yasutaka Hoshino, Wheaton, MD (US);

David M. Morens, Chevy Chase, MD (US);

Robert M. Chanock, Bethesda, MD (US);

John R. LA Montagne, Alexandria, VA (US);

Mary Elaine LA Montagne, Legal Representative, Alexandria, VA (US);

Brian R. Murphy, Bethesda, MD (US);

Inventors:

Albert Z. Kapikian, Rockville, MD (US);

Lone Simonsen, Chevy Chase, MD (US);

Timo Vesikari, Tampare, FI;

Yasutaka Hoshino, Wheaton, MD (US);

David M. Morens, Chevy Chase, MD (US);

Robert M. Chanock, Bethesda, MD (US);

John R. La Montagne, Alexandria, VA (US);

Mary Elaine La Montagne, legal representative, Alexandria, VA (US);

Brian R. Murphy, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/15 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides vaccine compositions for protection against human rotaviral disease designed for use in particular areas of the world. Human× bovine reassortant rotavirus comprising each of the four clinically most important VP7 serotypes of human rotavirus are combined with other VP7 serotypes typically found in the area of interest into a multivalent formulation which provides a high degree of infectivity and immunogenicity. Methods and an administration protocol for producing an immunogenic response without producing an increased risk of intussusception are also provided.


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