The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2012
Filed:
Aug. 10, 2009
Tasuku Honjo, Kyoto, JP;
Nagahiro Minato, Kyoto, JP;
Yoshiko Iwai, New York, NY (US);
Shiro Shibayama, Tsukuba, JP;
Tasuku Honjo, Kyoto, JP;
Nagahiro Minato, Kyoto, JP;
Yoshiko Iwai, New York, NY (US);
Shiro Shibayama, Tsukuba, JP;
ONO Pharmaceutical Co., Ltd., Osaka, JP;
Other;
Abstract
Compositions for cancer or infection treatment via immunopotentiation caused by inhibition of immunosuppressive signal induced by PD-1, PD-L1, or PD-L2 and therapies using them, immunopotentiative substrates included as the active ingredient, screening methods of the substrates for cancer or infection treatment, cell lines used for the screening methods, evaluation methods that select the substrates for cancer treatment, and carcinoma cell transplanted mammals used for the evaluation methods. The compositions of the present invention that inhibits the function of PD-1, PD-L1, or PD-L2 are useful for treatment of cancer or infection.