The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 01, 2012

Filed:

Aug. 03, 2007
Applicants:

Sung-ho Ryu, Pohang, KR;

Pann-ghill Suh, Pohang, KR;

Sang-hoon Ha, Pohang, KR;

Mi-nam Lee, Pohang, KR;

Hyun-ju Lee, Pohang, KR;

Il-shin Kim, Pohang, KR;

Do-hyung Kim, Minneapolis, MN (US);

Tae-hoon Lee, Pohang, KR;

Inventors:

Sung-Ho Ryu, Pohang, KR;

Pann-Ghill Suh, Pohang, KR;

Sang-Hoon Ha, Pohang, KR;

Mi-Nam Lee, Pohang, KR;

Hyun-Ju Lee, Pohang, KR;

Il-Shin Kim, Pohang, KR;

Do-Hyung Kim, Minneapolis, MN (US);

Tae-Hoon Lee, Pohang, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); C12N 9/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to method of regulating mammalian target-of-rapamycin (mTOR) based on a novel finding of a regulating mechanism of mTOR by a phospholipase D (PLD), and Ras homolog enriched in brain (Rheb). Further, the present invention also relates to a method of screening inhibitors of mTOR, and a method and a composition for treating mTOR-related metabolic diseases by inhibiting mTOR.


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