The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 24, 2012

Filed:

Jul. 16, 2010
Applicants:

Alan D Snow, Lynnwood, WA (US);

Beth Nguyen, Trophy Club, TX (US);

Gerardo Castillo, Bothell, WA (US);

Virginia Sanders, San Francisco, CA (US);

Thomas Lake, Snohomish, WA (US);

Lesley Larsen, Dunedin, NZ;

Rex T Weavers, Dunedin, NZ;

Stephen Lorimer, Dunedin, NZ;

David Larsen, Dunedin, NZ;

David L Coffen, San Diego, CA (US);

Charlotte Coffen, Legal Representative, Belcamp, MD (US);

Inventors:

Alan D Snow, Lynnwood, WA (US);

Beth Nguyen, Trophy Club, TX (US);

Gerardo Castillo, Bothell, WA (US);

Virginia Sanders, San Francisco, CA (US);

Thomas Lake, Snohomish, WA (US);

Lesley Larsen, Dunedin, NZ;

Rex T Weavers, Dunedin, NZ;

Stephen Lorimer, Dunedin, NZ;

David Larsen, Dunedin, NZ;

David L Coffen, San Diego, CA (US);

Charlotte Coffen, legal representative, Belcamp, MD (US);

Assignee:

ProteoTech, Inc., Kirkland, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 237/14 (2006.01); C07C 237/20 (2006.01); A61K 31/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.


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