The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 24, 2012

Filed:

Jun. 13, 2006
Applicants:

Wesley Peter Blackaby, Epping, GB;

Ian Thomas Huscroft, Bishops Stortford, GB;

Linda Elizabeth Keown, Belfast, GB;

Richard Thomas Lewis, Framingham, MA (US);

Piotr Antoni Raubo, West Bridgford, GB;

Leslie Joseph Street, Newport Beach, CA (US);

Christopher George Thomson, Billinghurst, GB;

Joanne Thomson, Cambridge, GB;

Inventors:

Wesley Peter Blackaby, Epping, GB;

Ian Thomas Huscroft, Bishops Stortford, GB;

Linda Elizabeth Keown, Belfast, GB;

Richard Thomas Lewis, Framingham, MA (US);

Piotr Antoni Raubo, West Bridgford, GB;

Leslie Joseph Street, Newport Beach, CA (US);

Christopher George Thomson, Billinghurst, GB;

Joanne Thomson, Cambridge, GB;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 303/00 (2006.01); C07C 233/00 (2006.01); C07C 237/00 (2006.01); C07C 323/00 (2006.01); A61K 31/16 (2006.01); A61K 31/165 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound of the formula (I): wherein R, R, R, R, Ar, A, n and m are defined herein, is disclosed as a GlyT1 inhibitor; pharmaceutical compositions containing the compound of the formula (I) are also disclosed as are their use in medicine, for example in the treatment of schizophrenia.


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