The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2012
Filed:
Jan. 25, 2007
Ylva Gravenfors, Sodertalje, SE;
Catrin Jonasson, Sodertalje, SE;
Jonas Malmstrom, Sodertalje, SE;
Gunnar Nordvall, Sodertalje, SE;
David Pyring, Sodertalje, SE;
Can Slivo, Sodertalje, SE;
Daniel Sohn, Sodertalje, SE;
Peter Strom, Sodertalje, SE;
David Wensbo, Lund, SE;
Ylva Gravenfors, Sodertalje, SE;
Catrin Jonasson, Sodertalje, SE;
Jonas Malmstrom, Sodertalje, SE;
Gunnar Nordvall, Sodertalje, SE;
David Pyring, Sodertalje, SE;
Can Slivo, Sodertalje, SE;
Daniel Sohn, Sodertalje, SE;
Peter Strom, Sodertalje, SE;
David Wensbo, Lund, SE;
AstraZeneca AB, Sodertalje, SE;
Abstract
The present invention relates to novel heteroaryl substituted benzothiazole derivatives, precursors thereof, and therapeutic uses for such compounds, having the structural formula (I) below: [Chemical formula should be inserted here. Please see paper copy] and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted benzothiazole derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.