The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 24, 2012

Filed:

Feb. 22, 2007
Applicants:

Peter Bernard Heifetz, San Diego, CA (US);

Blanca Llompart Royo, Barcelona, ES;

Pablo Marzábal Luna, Barcelona, ES;

Miriam Bastida Virgili, Molins de Rei, ES;

MA Dolores Ludevid Múgica, Sant Just Desvern, ES;

Margarita Torrent Quetglas, Barcelona, ES;

Kevin James O'connor, El Prat de Llobregat, ES;

Roser Pallisse Bergwerf, Valldoreix, ES;

MA Immaculada Ilop Tous, St. Feliu de Llobregat, ES;

Inventors:

Peter Bernard Heifetz, San Diego, CA (US);

Blanca Llompart Royo, Barcelona, ES;

Pablo Marzábal Luna, Barcelona, ES;

Miriam Bastida Virgili, Molins de Rei, ES;

Ma Dolores Ludevid Múgica, Sant Just Desvern, ES;

Margarita Torrent Quetglas, Barcelona, ES;

Kevin James O'Connor, El Prat de Llobregat, ES;

Roser Pallisse Bergwerf, Valldoreix, ES;

Ma Immaculada Ilop Tous, St. Feliu de Llobregat, ES;

Assignee:

ERA Biotech S.A., Barcelona, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/37 (2006.01); C07K 14/415 (2006.01); C07K 14/425 (2006.01); C12Q 1/34 (2006.01); C12Q 1/26 (2006.01);
U.S. Cl.
CPC ...
Abstract

A fusion protein that is expressed in a recombinant protein body-like assembly (RPBLA) in host eukaryotic cells and organisms is disclosed. More particularly, a biologically active polypeptide fused to a protein sequence that mediates the induction of RPBLA formation is expressed and accumulated in host cells after transformation with an appropriate vector. The eukaryotic host cell does not produce protein bodies in the absence of the fusion protein. Methods for preparing and using the RPBLAs and the fusion protein are also disclosed, as are nucleic acid molecules that encode the fusion proteins.


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