The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2012
Filed:
Jul. 31, 2009
Philippe Bergeron, San Francisco, CA (US);
Frederick Cohen, San Francisco, CA (US);
Anthony Estrada, San Carlos, CA (US);
Michael F. T. Koehler, Palo Alto, CA (US);
Kevin Hon Luen Lau, San Mateo, CA (US);
Cuong Ly, Daly City, CA (US);
Joseph P. Lyssikatos, Piedmont, CA (US);
Daniel Ortwine, San Ramon, CA (US);
Zhonghua Pei, Burlingame, CA (US);
Xianrui Zhao, San Mateo, CA (US);
Philippe Bergeron, San Francisco, CA (US);
Frederick Cohen, San Francisco, CA (US);
Anthony Estrada, San Carlos, CA (US);
Michael F. T. Koehler, Palo Alto, CA (US);
Kevin Hon Luen Lau, San Mateo, CA (US);
Cuong Ly, Daly City, CA (US);
Joseph P. Lyssikatos, Piedmont, CA (US);
Daniel Ortwine, San Ramon, CA (US);
Zhonghua Pei, Burlingame, CA (US);
Xianrui Zhao, San Mateo, CA (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
Disclosed are compounds of Formula I, including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, that are useful in modulating PIKK related kinase signaling, e.g., mTOR, and for the treatment of diseases (e.g., cancer) that are mediated at least in part by the dysregulation of the PIKK signaling pathway (e.g., mTOR).