The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2012
Filed:
Feb. 25, 2011
Stanley P. Pensak, Jr., East Walpole, MA (US);
John Heden, Hollis, NH (US);
Steven J. Ciavarini, Bellingham, MA (US);
John Lamoureux, Franklin, MA (US);
Miguel Soares, Norton, MA (US);
Stanley P. Pensak, Jr., East Walpole, MA (US);
John Heden, Hollis, NH (US);
Steven J. Ciavarini, Bellingham, MA (US);
John Lamoureux, Franklin, MA (US);
Miguel Soares, Norton, MA (US);
Waters Technologies Corporation, Milford, MA (US);
Abstract
Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream, to enhance chromatographic performance related to retention time and reproducibility. The preferred embodiment coordinates the injection run with active pressure control of a binary solvent delivery system to virtually eliminate the customary pressure drop when the low-pressure loop is brought on line. An additional benefit that enhances reproducibility is accomplished by forcing a consistent timing relationship between the injection run, the mechanical position of the delivery pump pistons, and the start and subsequent gradient delivery.