The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2012
Filed:
Oct. 31, 2008
Giacomo Vacca, Santa Clara, CA (US);
Richard G. Kendall, Miami, FL (US);
Norman R. Goldblatt, Los Altos, CA (US);
Michael W. Yee, Mount Shasta, CA (US);
Mahesh R. Junnarkar, San Jose, CA (US);
Giacomo Vacca, Santa Clara, CA (US);
Richard G. Kendall, Miami, FL (US);
Norman R. Goldblatt, Los Altos, CA (US);
Michael W. Yee, Mount Shasta, CA (US);
Mahesh R. Junnarkar, San Jose, CA (US);
Abbott Laboratories, Abbott Park, IL (US);
Abstract
A method for increasing the throughput, or the precision, or both the precision and the throughput, of a flow cytometer, or of a hematology analyzer employing a flow cytometer, and for further reducing the complexity of such a cytometer or analyzer, by utilizing the technique of laser rastering in combination with a lysis-free single-dilution method. Laser rastering involves sweeping a laser beam across a flowing sample stream in a hematology analyzer. A lysis-free single-dilution method involves performing all the flow cytometer measurements on a sample using a single aliquot, a single lysis-free reagent solution, a single dilution, and a single pass of said dilution through the measurement apparatus. An apparatus suitable for carrying out the method of this invention comprises an optical module comprising a source of light, a scanning device, a lens or system of lenses, a flowcell, detectors, and filters; and an electronic module comprising preamplifiers, analog signal conditioning elements, analog-to-digital converters, field-programmable gate arrays, digital signal processing elements, and data storage elements.