The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2012

Filed:

Feb. 13, 2009
Applicants:

Jeff Zablocki, Los Altos, CA (US);

Matthew Abelman, Mountain View, CA (US);

Michael Organ, Burlington, CA;

Yaroslav Bilokin, Toronto, CA;

Elfatih Elzein, Fremont, CA (US);

Tetsuya Kobayashi, Sunnyvale, CA (US);

Rao Kalla, Sunnyvale, CA (US);

Thao Perry, San Jose, CA (US);

Xiaofen LI, Mountain View, CA (US);

Robert Jiang, Milpitas, CA (US);

Ivan Diamond, Berkeley, CA (US);

Lina Yao, San Francisco, CA (US);

Peidong Fan, San Francisco, CA (US);

Maria Pia Arolfo, Pleasanton, CA (US);

Zhan Jiang, San Francisco, CA (US);

Wing Ming Keung, Wayland, MA (US);

Guoxin Tao, Brighton, MA (US);

Inventors:

Jeff Zablocki, Los Altos, CA (US);

Matthew Abelman, Mountain View, CA (US);

Michael Organ, Burlington, CA;

Yaroslav Bilokin, Toronto, CA;

Elfatih Elzein, Fremont, CA (US);

Tetsuya Kobayashi, Sunnyvale, CA (US);

Rao Kalla, Sunnyvale, CA (US);

Thao Perry, San Jose, CA (US);

Xiaofen Li, Mountain View, CA (US);

Robert Jiang, Milpitas, CA (US);

Ivan Diamond, Berkeley, CA (US);

Lina Yao, San Francisco, CA (US);

Peidong Fan, San Francisco, CA (US);

Maria Pia Arolfo, Pleasanton, CA (US);

Zhan Jiang, San Francisco, CA (US);

Wing Ming Keung, Wayland, MA (US);

Guoxin Tao, Brighton, MA (US);

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/35 (2006.01); C07D 307/77 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are novel isoflavone derivatives having the structure of Formula I which are useful as ALDH-2 inhibitors for treating mammals for dependence upon drugs of addiction, for example addiction to dopamine-producing agent such as cocaine, morphine, amphetamines, nicotine, and alcohol.


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