The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2012

Filed:

Mar. 28, 2011
Applicants:

Nils-gunnar Johansson, Huddinge, SE;

Genaidy Kalyanov, Huddinge, SE;

Joseph Armstrong Martin, Hertfordshire, GB;

David Bernard Smith, San Mateo, CA (US);

Anna Winqvist, Huddinge, SE;

Inventors:

Nils-Gunnar Johansson, Huddinge, SE;

Genaidy Kalyanov, Huddinge, SE;

Joseph Armstrong Martin, Hertfordshire, GB;

David Bernard Smith, San Mateo, CA (US);

Anna Winqvist, Huddinge, SE;

Assignee:

Medivir AB, Huddinge, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

4-Amino-1-((2R,3S,4S,5R)-5-azido-4-hydroxy-5-hydroxymethyl-3-methyl-tetrahydrofuran-2-yl)-1H-pyrimidin-2-one (22) and prodrugs thereof are hepatitis C (HCV) polymerase inhibitors. Also disclosed are compositions and methods for inhibiting HCV and treating HCV-mediated diseases, processes for making the compounds and synthetic intermediates employed in the process.


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