The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2012
Filed:
Feb. 22, 2008
Applicants:
Michael Boyd, Saint-Lazare, CA;
John Colucci, Kirkland, CA;
Yongxin Han, Kirland, CA;
Inventors:
Assignee:
Merck Canada Inc., Kirkland, Quebec, CA;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); A61K 31/437 (2006.01); C07D 209/08 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention is directed to indole and indoline cyclopropyl amide derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included.