The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2012
Filed:
Apr. 22, 2009
Miguel Medina Padilla, Madrid, ES;
Mercedes Alonso Cascon, Madrid, ES;
Isabel Dorronsoro Diaz, Madrid, ES;
Ana Martinez Gil, Madrid, ES;
Gema Panizo Del Pliego, Madrid, ES;
Ana Fuertes Huerta, Madrid, ES;
Maria Jose Perez Puerto, Madrid, ES;
Miguel Medina Padilla, Madrid, ES;
Mercedes Alonso Cascon, Madrid, ES;
Isabel Dorronsoro Diaz, Madrid, ES;
Ana Martinez Gil, Madrid, ES;
Gema Panizo Del Pliego, Madrid, ES;
Ana Fuertes Huerta, Madrid, ES;
Maria Jose Perez Puerto, Madrid, ES;
Noscira, S.A., , ES;
Abstract
Provided are thiadiazolidine compounds of formula I wherein Ris an organic group having at least 8 atoms selected from C or O, which is not linked directly to the N through a —C(O)— and comprising at least an aromatic ring, and their pharmaceutical compositions. These compounds are selective GSK-3 inhibitors and have improved bioavailability. They are useful for the treatment of GSK-3 mediated diseases, among others Alzheimer's disease, type II diabetes, depression and brain injury.