The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2012
Filed:
Dec. 21, 2010
Paul Allegretti, Fort Collins, CO (US);
Seok-ki Choi, Ann Arbor, MI (US);
Roland Gendron, San Francisco, CA (US);
Paul R. Fatheree, San Francisco, CA (US);
Keith Jendza, Boston, MA (US);
Robert Murray Mckinnell, Millbrae, CA (US);
Darren Mcmurtrie, Foster City, CA (US);
Brooke Olson, San Francisco, CA (US);
Paul Allegretti, Fort Collins, CO (US);
Seok-Ki Choi, Ann Arbor, MI (US);
Roland Gendron, San Francisco, CA (US);
Paul R. Fatheree, San Francisco, CA (US);
Keith Jendza, Boston, MA (US);
Robert Murray McKinnell, Millbrae, CA (US);
Darren McMurtrie, Foster City, CA (US);
Brooke Olson, San Francisco, CA (US);
Theravance, Inc., South San Francisco, CA (US);
Abstract
The invention is directed to compounds having the formula: wherein: Ar, r, R, X, and Rare as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have ATreceptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.