The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2012

Filed:

May. 29, 2008
Applicants:

Jeffrey M. Blaney, San Diego, CA (US);

Andreas Gosberg, San Diego, CA (US);

Stefan N. Gradl, San Diego, CA (US);

Gavin Hirst, San Diego, CA (US);

Stephanie A. Hopkins, San Diego, CA (US);

Paul A. Sprengeler, San Diego, CA (US);

Ruo W. Steensma, San Diego, CA (US);

Johnny UY, San Diego, CA (US);

Inventors:

Jeffrey M. Blaney, San Diego, CA (US);

Andreas Gosberg, San Diego, CA (US);

Stefan N. Gradl, San Diego, CA (US);

Gavin Hirst, San Diego, CA (US);

Stephanie A. Hopkins, San Diego, CA (US);

Paul A. Sprengeler, San Diego, CA (US);

Ruo W. Steensma, San Diego, CA (US);

Johnny Uy, San Diego, CA (US);

Assignee:

SGX Pharmaceuticals, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); A61K 31/5377 (2006.01); A61K 31/497 (2006.01); A61P 35/00 (2006.01); C07D 491/147 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided herein are substituted pyrrolopyridine heterocycles and substituted pyrazolopyridine heterocycles, pharmaceutical compositions comprising said heterocycles and methods of using said heterocycles in the treatment of disease. The heterocycles disclosed herein function as kinase modulators and have utility in the treatment of diseases such as cancer, allergy, asthma, inflammation, obstructive airway disease, autoimmune diseases, metabolic disease, infection, CNS disease, brain tumor, obesity, asthma, hematological disorder, degenerative neural disease, cardiovascular disease, or disease associated with angiogenesis, neovascularization, or vasculogenesis.


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