The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2012

Filed:

Sep. 14, 2007
Applicants:

Satoru Ohsuki, Chiba, JP;

Atsushi Tengeiji, Kanagawa, JP;

Masahiro Ikeda, Tokyo, JP;

Yoshihiro Shibata, Tokyo, JP;

Chikahiro Nagata, Tokyo, JP;

Takashi Shimada, Tokyo, JP;

Inventors:

Satoru Ohsuki, Chiba, JP;

Atsushi Tengeiji, Kanagawa, JP;

Masahiro Ikeda, Tokyo, JP;

Yoshihiro Shibata, Tokyo, JP;

Chikahiro Nagata, Tokyo, JP;

Takashi Shimada, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); A61K 31/415 (2006.01); C07D 491/00 (2006.01); C07D 487/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Problem to be Solved To provide a novel compound inhibiting the effect of HSP90, in particular a novel compound inhibiting the function of HSP90 as a chaperone protein and having antitumor activity. Solution The present invention provides a pyrazolopyrimidine compound represented by the formula (1) having various substituents which inhibits the ATPase activity of HSP90 and which has antitumor activity, an HSP90 inhibitor comprising the compound represented by the formula (1), a medicament comprising the compound represented by the formula (1), an anticancer agent comprising the compound represented by the formula (1), a pharmaceutical composition comprising the compound represented by the formula (1) and a method for treating cancer using the compound represented by the formula (1).


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