The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2012
Filed:
Jan. 25, 2011
Mark F. Pittenger, Severna Park, MD (US);
Stephen L. Gordon, Columbia, MD (US);
Alastair Morgan Mackay, Timonium, MD (US);
Bradley J. Martin, Ellicott City, MD (US);
Mark F. Pittenger, Severna Park, MD (US);
Stephen L. Gordon, Columbia, MD (US);
Alastair Morgan Mackay, Timonium, MD (US);
Bradley J. Martin, Ellicott City, MD (US);
Osiris Therapeutics, Inc., Baltimore, MD (US);
Abstract
Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.