The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2012
Filed:
Sep. 25, 2009
Applicant:
Stefan Hildbrand, Gelterkinden, CH;
Inventor:
Stefan Hildbrand, Gelterkinden, CH;
Assignee:
Hoffman-La Roche Inc., Nutley, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed is a process for the manufacture of pseudo proline dipeptides of the formula wherein Ris a side chain of an alpha amino acid, Ris an amino protecting group and Rand Rare independently selected from hydrogen or C-alkyl, Ris hydrogen or methyl starting from an amino acid derivative of the formula wherein Rand Rare as above. Pseudo proline dipeptides can be used as reversible protecting groups for Ser, Thr and Cys and thus are versatile tools in peptide chemistry.