The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2012

Filed:

Dec. 08, 2006
Applicants:

Antonin Holy, Prague, CZ;

Marcela Krecmerova, Prague, CZ;

Alois Piskala, Prague, CZ;

Graciela Andrei, Sint-Lambrechts-Woluwe, BE;

Robert Snoeck, Sint-Lambrechts-Woluwe, BE;

Erik DE Clercq, Bierbeek, BE;

Johan Neyts, Kessel-Lo, BE;

Lieve Naesens, Puurs, BE;

Inventors:

Antonin Holy, Prague, CZ;

Marcela Krecmerova, Prague, CZ;

Alois Piskala, Prague, CZ;

Graciela Andrei, Sint-Lambrechts-Woluwe, BE;

Robert Snoeck, Sint-Lambrechts-Woluwe, BE;

Erik De Clercq, Bierbeek, BE;

Johan Neyts, Kessel-Lo, BE;

Lieve Naesens, Puurs, BE;

Attorney:
Int. Cl.
CPC ...
C07F 9/38 (2006.01); C07F 9/40 (2006.01); C07F 9/42 (2006.01); A61K 31/675 (2006.01); A61P 31/20 (2006.01); A61P 31/22 (2006.01); C07D 251/46 (2006.01); C07D 251/52 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides 5-azacytosine derivatives with antiviral activity, specifically having viral replication inhibiting properties, more particularly in DNA viruses such as pox-, papilloma- and herpes viruses in humans. The invention also provides pharmaceutical compositions comprising such 5-azacytosine derivatives as active ingredients in combination with pharmaceutically acceptable carriers, which are useful for the treatment of subjects suffering from viral infections.


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