The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2012
Filed:
Nov. 04, 2009
Ekambar Kandimalla, Southboro, MA (US);
Mallikarjuna Putta, Burlington, MA (US);
Lakshmi Bhagat, Framingham, MA (US);
Daqing Wang, Bedford, MA (US);
Dong Yu, Westboro, MA (US);
Sudhir Agrawal, Shrewsbury, MA (US);
Ekambar Kandimalla, Southboro, MA (US);
Mallikarjuna Putta, Burlington, MA (US);
Lakshmi Bhagat, Framingham, MA (US);
Daqing Wang, Bedford, MA (US);
Dong Yu, Westboro, MA (US);
Sudhir Agrawal, Shrewsbury, MA (US);
Idera Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
Antisense oligonucleotide compounds, compositions and methods are provided for down regulating the expression of TLR5. The compositions comprise antisense oligonucleotides targeted to nucleic acids encoding TLR5. The compositions may also comprise antisense oligonucleotides targeted to nucleic acids encoding TLR5 in combination with other therapeutic and/or prophylactic compounds and/or compositions. Methods of using these compounds and compositions for down-regulating TLR5 expression and for prevention or treatment of diseases wherein modulation of TLR5 expression would be beneficial are provided.