The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2012
Filed:
Jan. 08, 2010
Applicants:
Michael Blaber, Tallahassee, FL (US);
Vikash Kumar Dubey, Guwahati, IN;
Inventors:
Michael Blaber, Tallahassee, FL (US);
Vikash Kumar Dubey, Guwahati, IN;
Assignee:
Florida State University Research Foundation, Inc., Tallahassee, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/18 (2006.01); C07K 14/50 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
Abstract
Mutants of human FGF-1 are disclosed having increased stability and mitogenic potency. In the FGF-1 polypeptide, primarily residue 12 is substituted with threonine and/or residue 134 is substituted cysteine, valine or threonine to render the polypeptide more stable and/or to increase its mitogenecity.