The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2012
Filed:
Oct. 24, 2008
Applicants:
Jun Xu, Edmond, OK (US);
Charles Esmon, Oklahoma City, OK (US);
Inventors:
Jun Xu, Edmond, OK (US);
Charles Esmon, Oklahoma City, OK (US);
Assignee:
Oklahoma Medical Research Foundation, Oklahoma City, OK (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides monoclonal antibodies that selectively bind to and inhibit activated protein C without binding to or inhibiting unactivated protein C. Other antibodies inhibit both activated protein C and activation of unactivated protein C. Methods of treatment employing these antibodies are described herein as are methods of screening for and detecting these antibodies.