The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2012

Filed:

Jan. 05, 2009
Applicants:

Bing-yan Zhu, Palo Alto, CA (US);

Shawn M. Bauer, Pacifica, CA (US);

Zhaozhong J. Jia, San Mateo, CA (US);

Gary D. Probst, San Francisco, CA (US);

Yanchen Zhang, Union City, CA (US);

Robert M. Scarborough, Half Moon Bay, CA (US);

Inventors:

Bing-Yan Zhu, Palo Alto, CA (US);

Shawn M. Bauer, Pacifica, CA (US);

Zhaozhong J. Jia, San Mateo, CA (US);

Gary D. Probst, San Francisco, CA (US);

Yanchen Zhang, Union City, CA (US);

Robert M. Scarborough, Half Moon Bay, CA (US);

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); A61K 31/4164 (2006.01); A61K 31/4192 (2006.01); C07D 249/04 (2006.01); C07D 233/66 (2006.01); C07D 207/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.


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