The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2012
Filed:
Nov. 17, 2005
Applicants:
Xiao-yi Xiao, San Diego, CA (US);
Dinesh V. Patel, Fremont, CA (US);
Inventors:
Xiao-Yi Xiao, San Diego, CA (US);
Dinesh V. Patel, Fremont, CA (US);
Assignee:
Miikana Therapeutics, Inc., Rockville, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 239/553 (2006.01); A61K 31/4155 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed are protein kinase inhibitors of Formula Ia and Ib, compositions comprising such inhibitors, and methods of use, thereof. More particularly, these compounds and compositions are inhibitors of Aurora-A (Aurora-2) and Aurora-B (Aurora-1) protein kinase. Also disclosed are methods of using these compounds and compositions to prevent and treat diseases associated with protein kinases, especially diseases associated with Aurora-A or Aurora-B, such as cancer.