The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8153585 B1

PDF
Full Text
Expired
Date of Patent:
Apr. 10, 2012

Filed:

Jul. 14, 2008
Applicants:

Michael Klagsbrun, Newton, MA (US);

Shay Soker, Greensboro, NC (US);

Inventors:

Michael Klagsbrun, Newton, MA (US);

Shay Soker, Greensboro, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/475 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides isolated polypeptides having VEGF antagonist activity, pharmaceutical compositions and methods of treatment of subjects having a disease or disorder associated with VEGF activity or subjects having tumors expressing a VEGF receptor. The polypeptides of the invention include polypeptides comprising a portion of SEQ ID NO: 1 having VEGF antagonist activity, polypeptides comprising SEQ ID NO: 2 or a portion thereof having VEGF antagonist activity, and a polypeptide having the structure of formula (I), set forth above. The present invention further includes analogs and derivatives of these polypeptides having VEGF antagonist activity.


Find Patent Forward Citations

Klagsbrun, Michael. (2012). Peptide antagonists of vascular endothelial growth factor and methods of use thereof (U.S. Patent No. 8153585). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8153585

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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