The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2012
Filed:
May. 09, 2008
Kent D. Taylor, Ventura, CA (US);
Jerome I. Rotter, Los Angeles, CA (US);
Charles O. Elson, Birmingham, AL (US);
Stephan R. Targan, Santa Monica, CA (US);
Kent D. Taylor, Ventura, CA (US);
Jerome I. Rotter, Los Angeles, CA (US);
Charles O. Elson, Birmingham, AL (US);
Stephan R. Targan, Santa Monica, CA (US);
Cedars-Sinai Medical Center, Los Angeles, CA (US);
The UAB Research Foundation, Birmingham, AL (US);
Abstract
This invention provides methods of diagnosing or predicting susceptibility to Crohn's Disease by determining the presence or absence of genetic variants. In one embodiment, the present invention provides methods to diagnose and/or predict susceptibility to Crohn's Disease in an individual by determining the presence or absence of anti-Cbir1 reactivity and the presence or absence of TLR5 risk variants. In another embodiment, the present invention provides methods to diagnose Crohn's Disease by determining the presence or absence of NFKB1 haplotype H3 and/or ASCA expression. In another embodiment, the present invention provides methods of diagnosing Crohn's Disease by determining the presence or absence of Cbir1 specific peripheral blood T cell proliferation.