The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2012
Filed:
Oct. 21, 2009
Alan R. Craig, Wilmington, DE (US);
Zhu Teng, Boothwyn, PA (US);
Carsten Schelp, Hockessin, DE (US);
Jason Snyder, Newark, DE (US);
Christine Moran, Elkton, MD (US);
Alan R. Craig, Wilmington, DE (US);
Zhu Teng, Boothwyn, PA (US);
Carsten Schelp, Hockessin, DE (US);
Jason Snyder, Newark, DE (US);
Christine Moran, Elkton, MD (US);
Siemens Healthcare Diagnostics Inc., Deerfield, IL (US);
Abstract
Methods and reagents are disclosed for conducting assays. Embodiments of the present methods and reagents are concerned with a solid support such as, for example, a particle. The support includes a chemiluminescent composition that includes a metal chelate. The present inventors observed that, when such support such as, e.g., particles, were employed in assays for the determination of an analyte, stability of signal output by the chemiluminescent composition associated with the particle was unacceptably reduced as compared to particles including other chemiluminescent compositions. In accordance with embodiments of the present invention, the stability of signal output from such particles is enhanced by including in a medium that contains the particles a sufficient amount of one or more stabilizing agents, which may be a chelating agent and/or a metal chelate such as, for example, the metal chelate that is associated with the particle.