The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2012
Filed:
May. 25, 2007
Margus Lopp, Tallinn, EE;
Anne Paju, Tallinn, EE;
Margus Eek, Harjumaa, EE;
Marit Laos, Tallinn, EE;
Tonis Pehk, Tallinn, EE;
Raissa Jaalaid, Tallinn, EE;
Margus Lopp, Tallinn, EE;
Anne Paju, Tallinn, EE;
Margus Eek, Harjumaa, EE;
Marit Laos, Tallinn, EE;
Tonis Pehk, Tallinn, EE;
Raissa Jaalaid, Tallinn, EE;
Tallinn University of Technology, Tallinn, EE;
Cambrex Tallinn AS, Tallinn, EE;
Abstract
Archiral (2-hydroxy-3-oxo-cyclopent-1-enyl) acetic acid) alkyl, alkylphenyl and phenyl esters, and a simple and efficient method for the synthesis of both enantiomers of homocitric acid gamma-lactone and the corresponding salts from these esters are described. The method is based on asymmetric oxidation of esters, and the steps of basic and acidic hydrolysis and final acidic lactonization of the homocitric acid into homocitric acid gamma-lactone. The homocitric acid salts are obtained after basic treatment of homocitric acid gamma-lactone. The esters, conditions and reagents used in chemical conversion and separating products are important constituents affording efficient and simple method for production of homocitric acid gamma-lactone and homocitric acid salts.